Caleb Ellington

@probablybots

Virtual Cell wrangler @genbioai | PhD @CMUCompBio | Creator contextualized.ml | context-adaptive models, disease simulators, personalized medicine

San Francisco, CA

Pinned
Caleb Ellington
@probablybots
May 27, 2025
Honored to share a major thread of my PhD research, out now in PNAS. We address a core issue with how models are used for scientific discovery. Models are so important that they define the entire scientific process... 1/n
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Caleb Ellington
@probablybots
Sep 3
Can I make Fable fall back to Opus 4.6
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Caleb Ellington
@probablybots
Aug 18
GenBio was founded with the audacious goal of simulating all of biology. The natural starting point for biological simulation is the cell: the smallest unit of life. Today we're sharing a preview of our first version of that simulator, AIDO Cell.
GenBio AI
@genbioai
Aug 18
01:56
Today we're releasing a preview of AIDO Cell, a world model of the human cell. It simulates one cell across DNA, RNA, protein, through regulatory networks and whole-cell behavior. Not four models handing results to each other. One system.
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Caleb Ellington
@probablybots
Jul 31
Statistical estimation is being absorbed into context. In a new 90-page review, we provide a unified view of statistical and foundation models through the lens of context-adaptive inference! ...
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Caleb Ellington
@probablybots
Jul 29
Opus 5 is a terrible writer. I went back to Opus 4.6 to see if it was always this bad. The difference is night and day.