Profluent

@ProfluentBio

Grounded in nature, authored by AI

Emeryville, CA

profluent.bio

Joined September 2022

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4,163 Followers

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Profluent
@ProfluentBio
Nov 19, 2025
Today we’re announcing $106M in new funding led by Altimeter Capital and Bezos Expeditions. This brings our total to $150M to scale our frontier AI models which make biology programmable. Our frontier models have generated functional proteins (Nature Biotech, 2023), created the
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Profluent
@ProfluentBio
Sep 30
We’re partnering with @BioMarin to use our AI models to design novel medicines. Our foundation models unlock proteins with new and improved functions by drawing on the world's largest dataset of unique protein sequences (115B and counting): Profluent’s Protein Atlas BioMarin
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Profluent
@ProfluentBio
Aug 12
Stephen Nayfach, our Head of Bioinformatics and Platform R&D, is at @CSHL this week for the Genome Engineering: CRISPR Frontiers event. Find him and say hi if you're there! 👋 He's giving a talk on using our AI models to design CRISPR-Cas9 variants for base editing ("Programming
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Profluent
@ProfluentBio
Jul 30
The Profluent team is heading to Summer RosettaCon next week! Find @jeffruffolo, @richardwshuai, @ShiakiMinami, and Alex Hoffnagle and say hi 👋 You can hear Richard talk about E1, our encoder model, on Thur at 1:30pm (“E1: Retrieval-Augmented Protein Encoders for Fitness and
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Profluent
@ProfluentBio
Jul 9
A suite of AI-designed base editors, all from one scaffold. The only piece unique to each patient is the guide RNA. That's the shift AI unlocks: rare disease moves from 'one drug at a time' to a platform, built to bring cost down and reach more patients. More on our work with
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